BDBM50410807 POLUMYXIN B::POLYMIXIN B::POLYMYXIN B

SMILES CCC(C)CCCCC(=O)N[C@@H](CCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCN)C(=O)N[C@H]1CCNC(=O)[C@@H](NC(=O)[C@H](CCN)NC(=O)[C@H](CCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](CCN)NC1=O)[C@@H](C)O

InChI Key InChIKey=WQVJHHACXVLGBL-BPJDFBQWSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50410807   

TargetToll-like receptor 4(Homo sapiens (Human))
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50410807(POLUMYXIN B | POLYMIXIN B | POLYMYXIN B)
Affinity DataIC50:  1.23E+3nMAssay Description:Inhibition of induction of NF-kappaB by LPS in HEK293 cells co-transfected with TLR4, CD14 and MD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed